Cajun Beef Linguine in Creamy Velveeta Parmesan Garlic Sauce

by Nina Johnson July 26, 2025

Rich, creamy, and unapologetically indulgent, this Cajun Beef Linguine in Velveeta Parmesan Garlic Sauce is what comfort food dreams are made of. Think bold Cajun spices meeting tender ground beef, all tangled in silky strands of linguine coated with a cheesy, garlicky sauce that clings to every bite.

This dish balances heat and creaminess with ease, thanks to the blend of Velveeta and Parmesan that melts into a savory garlic cream sauce. Whether you’re feeding a hungry family or just craving something soul-satisfying on a chilly night, this pasta brings restaurant-style decadence right to your kitchen.

What Kind of Linguine or Beef Should I Use?

For this recipe, classic durum wheat linguine works beautifully—it holds onto the creamy sauce perfectly and offers a satisfying chew. If you’re after a bit more flavor or heartiness, feel free to use whole wheat or even spinach linguine. When it comes to the beef, a lean ground beef (80/20) gives you the ideal mix of richness and tenderness without excess grease.

If you’d rather go lighter or switch it up, ground turkey or chicken seasoned well with Cajun spice can easily be substituted.

Ingredients for the Cajun Beef Linguine in Creamy Velveeta Parmesan Garlic Sauce

Linguine Pasta – The base of the dish, perfect for absorbing that cheesy garlic sauce.
Ground Beef – Adds hearty, savory flavor and protein to make it a complete meal.
Velveeta Cheese – The star for meltability and creaminess, blending seamlessly into the sauce.
Parmesan Cheese – Brings a sharp, salty edge that complements the Velveeta.
Heavy Cream – The luscious base of the sauce that ties all the flavors together.
Minced Garlic – Adds aromatic depth and a savory bite to the sauce.
Cajun Seasoning – Delivers bold, spicy flavor that defines the personality of the dish.
Butter – Helps cook the garlic and adds richness to the sauce.
Crushed Red Pepper (optional) – For those who like a little extra heat.
Fresh Parsley or Dried Herbs – A finishing touch for color and freshness.

How To Make the Cajun Beef Linguine in Creamy Velveeta Parmesan Garlic Sauce

Step 1: Boil the Pasta

Bring a large pot of salted water to a boil. Cook the linguine until al dente according to package instructions. Drain and set aside.

Step 2: Brown the Ground Beef

In a large skillet over medium-high heat, cook the ground beef until browned and no longer pink. Break it apart with a spatula as it cooks. Drain excess grease if necessary, then set the meat aside.

Step 3: Sauté Garlic in Butter

In the same skillet, melt butter over medium heat. Add the minced garlic and sauté for about 1 minute until fragrant, making sure it doesn’t burn.

Step 4: Make the Creamy Sauce

Pour in the heavy cream and stir in the Velveeta cheese cubes. Keep stirring until the cheese is fully melted and the sauce becomes smooth and creamy. Add the Parmesan cheese and Cajun seasoning. Stir to combine.

Step 5: Combine Everything

Return the ground beef to the skillet and toss in the cooked linguine. Mix until the pasta is fully coated with the sauce. Add crushed red pepper if you want more kick.

Step 6: Garnish and Serve

Sprinkle with chopped parsley or dried herbs and serve immediately while hot and creamy.

Serving and Storing Cajun Beef Linguine

This dish is best enjoyed fresh off the stove when the sauce is velvety and the flavors are bold. Serve with garlic bread or a crisp green salad to round out your meal. If you have leftovers, store them in an airtight container in the refrigerator for up to 3 days. Reheat gently on the stovetop or in the microwave with a splash of cream to restore creaminess.

Frequently Asked Questions

How spicy is this Cajun pasta?

The spice level is moderate, thanks to Cajun seasoning. You can always adjust the heat by adding more or less crushed red pepper.

Can I make this recipe ahead of time?

Yes, but for best texture, cook the pasta and sauce separately and combine them right before serving.

What can I use instead of Velveeta?

You can substitute with cream cheese or shredded cheddar, but Velveeta melts smoother and gives that classic creamy texture.

Is this recipe freezer-friendly?

It’s best fresh, but you can freeze it in portions. The sauce may separate slightly upon reheating, so stir well and reheat slowly.

Can I add vegetables?

Absolutely! Bell peppers, mushrooms, or spinach would pair beautifully with the Cajun flavors and creamy sauce.

Want More Pasta Ideas?

If you love this creamy Cajun linguine, here are some other pasta recipes worth twirling your fork into:

📌 Save this recipe to your Pinterest dinner board so you can come back to it any time.

And let me know in the comments how yours turned out! Did you go all-in with Cajun spice? Maybe added mushrooms or swapped the protein? I love hearing how others put their spin on this dish.

Need more cheesy dinner inspiration? Follow me on Pinterest at Life with Nina for more indulgent, cozy meals!