One-Pot Creamy Cajun Chicken Linguine with Garlic Mozzarella Sauce

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There’s something irresistibly comforting about a bowl of creamy, cheesy pasta wrapped around tender, flavorful chicken. This One-Pot Creamy Cajun Chicken Linguine is everything you want in a weeknight dinner—bold flavor, minimal cleanup, and pure indulgence in every bite. The linguine is cooked in the same pot as the seared Cajun-spiced chicken and the garlic mozzarella cream sauce, making it not just easy, but extra flavorful.

The beauty of this dish is in the balance: a smoky Cajun crust on juicy chicken, paired with silky linguine coated in a rich, garlicky mozzarella sauce. It’s the kind of dinner that makes people ask for seconds (or thirds). Perfect for cozy nights or whenever you want to treat yourself with something satisfying and homemade.

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What Kind of Cajun Seasoning Should I Use?

Go for a Cajun seasoning that brings heat but doesn’t overwhelm. Look for a blend that balances paprika, garlic powder, onion powder, cayenne, and herbs. Store-bought mixes work great, but if you have time, mix your own for more control over the spice level. This way, you can cater it to your household’s heat preference—mild or extra bold.

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Ingredients for the One-Pot Creamy Cajun Chicken Linguine

Chicken Breast: Lean, juicy, and perfect for taking on bold Cajun flavors. You’ll want thin-sliced or pounded flat for quick, even cooking.

Linguine: Its flat shape holds onto the sauce beautifully, delivering creamy bites from start to finish.

Cajun Seasoning: The star of the dish. It infuses the chicken with smoky, spicy depth.

Butter & Olive Oil: Used together for searing the chicken with both flavor and crispness.

Garlic: Adds depth and aroma to the sauce; fresh minced garlic is key.

Heavy Cream: Brings the creamy richness to the dish and binds the sauce.

Mozzarella Cheese: Melts into the cream for that luscious, cheesy sauce we all crave.

Parmesan Cheese: Adds a nutty saltiness that balances the richness of the cream.

Chicken Broth: Enhances the savory base of the sauce without overpowering.

Sun-dried Tomatoes (optional): A pop of tang and sweetness that pairs well with the creamy base.

Fresh Parsley: For a fresh finish and a bit of color.

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How To Make the One-Pot Creamy Cajun Chicken Linguine

Step 1: Season and Sear the Chicken

Generously coat the chicken breasts with Cajun seasoning on both sides. Heat butter and olive oil in a large skillet or Dutch oven over medium-high heat. Sear the chicken until golden and fully cooked through (about 4–5 minutes per side). Remove from the pan and let rest before slicing.

Step 2: Sauté the Garlic

Lower the heat to medium and add a bit more butter if needed. Toss in the minced garlic and cook for 30 seconds to a minute, just until fragrant. Don’t let it brown.

Step 3: Build the Creamy Sauce

Pour in the heavy cream and chicken broth, stirring to combine. Bring the mixture to a gentle simmer, then slowly add the mozzarella and parmesan, stirring until completely melted and the sauce is smooth.

Step 4: Cook the Linguine

Add the dry linguine directly into the pot. Stir frequently to ensure even cooking and to prevent sticking. Simmer gently until the pasta is al dente and the sauce has thickened, about 10–12 minutes. Add a splash more broth or water if the sauce gets too thick.

Step 5: Add Final Touches

Stir in sun-dried tomatoes if using, and adjust seasoning with salt and pepper. Return sliced chicken to the pot or place it over the linguine. Garnish with fresh parsley and serve hot.

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How to Serve and Store This Creamy Cajun Chicken Linguine

Serve this dish hot, straight from the pot, with a sprinkle of fresh parsley or extra parmesan. A slice of crusty garlic bread or a simple green salad on the side can round it out into a complete meal.

To store leftovers, let the pasta cool completely before transferring to an airtight container. It keeps well in the refrigerator for up to 3 days. When reheating, add a splash of cream or broth to loosen the sauce and keep it silky.

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Frequently Asked Questions

Can I use another type of pasta?

Yes! While linguine works beautifully here, you can use fettuccine, spaghetti, or even penne. Just adjust the liquid slightly and keep an eye on the cooking time.

Is this recipe spicy?

The heat depends on your Cajun seasoning. If you’re spice-sensitive, choose a milder blend or use less. You can always add more spice at the end.

Can I substitute the chicken with shrimp?

Absolutely. Cajun shrimp is a fantastic alternative. Just reduce the cooking time, as shrimp cook much faster than chicken.

What if I don’t have mozzarella?

You can substitute with Monterey Jack or even cream cheese for a different creamy texture, though the flavor will slightly vary.

Can I make this dish ahead of time?

It’s best fresh, but you can prep the chicken and sauce earlier in the day. Cook the pasta just before serving for the creamiest result.

Is this freezer-friendly?

It’s not ideal for freezing due to the cream base. The sauce can separate when reheated from frozen. Stick to fridge storage for best results.

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Want More Pasta Dinner Ideas?

If you loved this One-Pot Creamy Cajun Chicken Linguine, here are a few other dishes you should absolutely try next:

• Garlic Butter Chicken with Creamy Ricotta Alfredo Pasta – ultra-rich with a touch of tang.
• One-Pot Chicken Parmesan Mac & Cheese – cozy comfort with a crispy topping.
• One Skillet Spicy Buffalo Ranch Chicken Pasta – a zesty kick in every bite.
• Cowboy Butter Chicken Linguine – garlicky, buttery, and bold.
• Cajun Ranch Shrimp and Sausage Pasta Skillet – layers of smoky, creamy flavor in one pan.

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Save This Pin + Share Your Results

📌 Save this recipe to your Pinterest dinner board so you can come back to it any time.

And let me know in the comments how yours turned out! Did you swap the linguine for fettuccine? Try shrimp instead of chicken?

I love seeing how you make these recipes your own. If you have a question or twist to share, drop it below—we’re all learning together.

For more crave-worthy meals like this, check out my Pinterest board at Life with Nina where I post new daily favorites.

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